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Products - Microarray Scanners - Laser Scanners - Arrayit InnoScan® 910, 910AL and 1100AL High Speed Fluorescence Microarray Scanners

InnoScan
Arrayit InnoScan® 910, 910AL and 1100AL high-performance microarray scanners comprise the newest instruments in our laser scanning series. These compact, desktop instruments feature proprietary rotary motion control for superior speed and durability, complete controller and Mapix® quantification and data analysis software, dynamic auto-focusing for superior precision, and two-color (910 and 910AL) and three-color (1100AL) detection. The 1100AL is our top-of-the-line scanner featuring 488 nm (FITC), 532 nm (cyanine 3) and 635 nm (cyanine 5) three-color scanning and a world’s best 0.5 µm scan resolution for microarray and tissue microarray applications in research and clinical laboratories leveraging genomics, proteomics, diagnostics and pharmaceutical drug discovery.

Arrayit-910AL
Figure 1. Arrayit InnoScan 910, 910AL and 1100AL Microarray Scanners are ideal for low- and medium-density two-color DNA microarrays for comparative gene expression analysis of test and control samples. Two-color microarrays offer the market’s most rapid and affordable means of identifying genes involved in human disease onset and progression, drug mode of action and many other pathways.

Arrayit 1100AL
Figure 2. Arrayit InnoScan 910, 910AL and 1100AL Microarray Scanners support a wide variety of 1 x 25 x 76 mm glass substrate slides including silane-activated glass, nitrocellulose-coated glass and slides with other membranes, SuperMask and other microarray dividers, and popular formats from major suppliers including Arrayit, Agilent and Schott.

innoscan 910
Figure 3. Arrayit InnoScan 910, 910AL and 1100AL Microarray Scanners support the growing protein microarray industry including antigen, antibody, peptide, and reverse phase cell lysate microarrays for protein expression assays, protein binding studies, drug discovery, serum-based immunoassays and many others.

innoscan-1100
Figure 4. Arrayit InnoScan 910, 910AL and 1100AL Microarray Scanners empower high-density DNA and protein microarray analysis including chips with hundreds of thousands to millions of individual features. The 910 and 910AL and the 1100AL instruments utilize 1.0 µm and 0.5 µm scan resolution, respectively, to rapidly interrogate the human genome and proteome in a highly accurate and cost-effective manner.

Arrayit InnoScan 910 910AL
Figure 5. Arrayit InnoScan 910 and 910AL high-speed microarray scanners offer two-color 532 nm and 635 nm detection, 1 µm scan resolution and single substrate slide (910) and 24-slide autoloader (910AL) for exceptional performance and ease-of-use in compact desktop scanners. All systems are equipped with a BioBlue Personal Computer, Mapix® quantification and analysis software, and complete cables and accessories for 30-minute setup time and years of reliable performance.

Table 1. Arrayit InnoScan® 910, 910AL and 1100AL Microarray Scanner Specifications.

Specification

Arrayit InnoScan® 910 and 910AL

Arrayit InnoScan® 1100AL

General Description

Characterized by simplicity of use, competitive price and superior image quality, Arrayit® InnoScan® 910 scanners are ideal instruments for scanning most high density microarrays available on the market. The single substrate slide (910) and 24-substrate  slide autoloader (910AL) scanners feature high resolution 1 µm scanning, high speed 3.5 min per slide 10 µm scan time, reliable and traceable results with barcode reading, comprehensive Mapix image quantification and analysis software, and proprietary high-speed Arrayit BioBlue Computing to manage the 5.74 GB data files produced by 1 µm scanning.

Characterized by ease of use, performance and versatility, the Arrayit InnoScan 1100AL is an ideal instrument for high density DNA, protein, tissue and whole cell microarrays and one-, two- and three-color applications. The 24-substrate slide autoloader 1100AL features a market-leading 0.5 µm scan resolution equivalent to a 20x optical objective, high speed 3.5 min per slide 10 µm scan time, reliable and traceable results with barcode reading, real-time auto-focusing, confocal PMT detection, user-friendly Mapix image acquisition and analysis software, and proprietary high-speed Arrayit BioBlue Computing to manage the 22.96 GB data files produced by 0.5 µm scanning.

Applications

Arrayit InnoScan 910 and 910AL instruments are ideal for scanning most low-, medium- and high-density microarrays currently available on the market for genotyping, gene expression comparative genomic hybridization (CGH), copy number variation (CNV), DNA methylation, miRNA studies, carbohydrate microarrays, antigen and antibodiy microarrays, proteomics and many other appolications.

The Arrayit InnoScan 1100AL instrument is ideal for rapid and high-performance automated scanning of low-, medium- and high-density microarrays containing DNA, peptides, antibodies, microenvironment sensors, transfected cells, glycans and many other sample types for genotyping, gene expression, comparative genomic hybridization (CGH), copy number variation (CNV), DNA methylation, miRNA studies, biomarker identification, human diseaes analysis, tissue microarray (TMA), tissue immunofluorescence for one-, two- and three-color applications in research, life sciences, diagnostics, pharmaceuticals and other areas.

Technology

Arrayit InnoScan® 910 and 910AL instruments leverage confocal scanning, two lasers, two extremely sensitive analog photomultiplier tubes (PMT), and linear gain from 0.1-100%. Full PMT control makes it easy to adjust scanner sensitivity to read the complete range of microarray signal intensities. Real-time auto-focusing ensures scan uniformity across the entire substrate slide. Extended Dynamic Range (XDR) and 20-bit TIFF images enable dynamic range exceeding 1 x 10^6 and detection of the dimmest signals while avoiding saturation. The 910 and 910AL have excellent photometric properties, particularly in terms of sensitivity and signal-to-noise ratio.

The Arrayit InnoScan® 1100AL instrument leverages confocal scanning, three lasers, three extremely sensitive analog photomultiplier tubes (PMT), and linear gain from 1-100%. Full PMT control makes it easy to adjust scanner sensitivity to read the complete range of microarray signal intensities. Real-time auto-focusing ensures scan uniformity across the entire substrate slide. Extended Dynamic Range (XDR) and 20-bit TIFF images enable dynamic range exceeding 1 x 10^6 and detection of the dimmest signals while avoiding saturation. The 1100AL has excellent photometric properties, particularly in terms of sensitivity and signal-to-noise ratio.

Resolution

1-40 µm per pixel

0.5-40 µm per pixel

Excitation wavelength

532 nm and 635 nm

488 nm, 532 nm and 635nm

Compatible fluorophores

532 nm: Cy3, Alexa 546, Alexa 555
635 nm: Cy5, Alexa 647, Alexa 660

488 nm: Cy2, Alexa488, FITC
532 nm: Cy3, Alexa 546, Alexa 555, Sytox orange
635 nm: Cy5, Alexa 647, Alexa 660, Draq5

Microarray format

Standard glass substrate slide format 1 x 25 x 76 mm

Standard glass substrate slide format 1 x 25 x 76 mm

Maximal scan area

22  x 74 mm

22  x 74 mm

Focus

Automatic or manual

Automatic or manual

Detection

Analog PMT and true confocal detection

Analog PMT and true confocal detection

PMT gain

Linear from 0.1 to 100%
Possible gain < 1% with 0.01 step

Linear from 1 to 100%

Scanning mode

Simultaneous or sequential

Simultaneous or sequential

Scanning speed

10 to 35 lines per second

10 to 35 lines per second

Scanning time

3.5 minutes to scan a whole slide at 10 µm per pixel resolution

3.5 minutes to scan a whole slide at 10 µm per pixel and 3 colors
10.5 minutes for an area of 22 x 22 mm at 1 µm per pixel and 3 colors

Dimensions

32 x 55 x 43 cm  (12.6” x 21.7” x 16.9” for the 910
33 x 66 x 44 cm3 (13” x 26” x 17.3”) for the 910AL

33 x 66 x 44 cm3 (13” x 26” x 17.3”) for the 1100AL

Weight

28 Kg (62 lbs) for the 910
38 Kg (83.6 lbs) for the 910AL

39 Kg (85.8 lbs) for the 1100AL

Interface

Ethernet

Ethernet

Barcode scanner

Yes

Yes

Image analysis and processing software

Mapix®

Mapix®

Image file format

16-bit and 20-bit TIFF

16-bit and 20-bit TIFF

Autoloader

24-slide automated (910AL)

24-slide automated

Arrayit scanner
Figure 6. Arrayit InnoScan 910, 910AL and 1100AL Microarray Scanners feature compact benchtop designs to permit user-friendly operation in a wide range of laboratory environments including research facilities and class 1 cleanroom manufacturing and testing centers.

peptide-array
Figure 7. Arrayit InnoScan 1100AL Microarray Scanner data image for a high density peptide microarray containing 10 µm feature size, 16 µm spacing and 440,000 peptide features per square centimeter. Data courtesy Dr. Alexander Nesterov-Muller, Institute of Microstructure Technology (IMT), Eggenstein-Leopoldshafen, Germany.

Ordering Information

Product

Description

Catalog ID

Price (US Dollars)*

Arrayit InnoScan® 910 Microarray Scanner

Arrayit® InnoScan® 910 scanners are ideal instruments for scanning most low-, medium- and high-density microarrays available on the market, offering user-friendly software, competitive pricing and superior image quality.  The single substrate slide 910 scanner features high resolution 1 µm scanning, two color 532 nm and 635 nm detection, high speed 3.5 min per slide 10 µm scan time, reliable and traceable results with barcode reading, comprehensive Mapix image quantification and analysis software, and proprietary high-speed Arrayit BioBlue Computer to manage the 5.74 GB data files produced by 1 µm scanning, 22” LED screen, keyboard, mouse, mouse pad, calibration slide and cables.

910

$76,896
Purchase1

Arrayit InnoScan® 910AL Microarray Scanner

Arrayit® InnoScan® 910AL scanners are ideal automated instruments for scanning most low-, medium- and high-density microarrays available on the market, offering user-friendly software, competitive pricing and superior image quality. The 24- substrate slide 910AL scanner features high resolution 1 µm scanning, two color 532 nm and 635 nm detection, 24-slide autoloader, high speed 3.5 min per slide 10 µm scan time, reliable and traceable results with barcode reading, comprehensive Mapix image quantification and analysis software, and proprietary high-speed Arrayit BioBlue Computer to manage the 5.74 GB data files produced by 1 µm scanning, 22” LED screen, keyboard, mouse, mouse pad, calibration slide and cables.

910AL

$91,584
Purchase1

Arrayit InnoScan® 1100AL Microarray Scanner

Arrayit® InnoScan® 1100AL scanners are the ultimate automated instruments for scanning most low-, medium- and high-density microarrays and tissue microarrays (TMAs) available on the market offering user-friendly software, competitive pricing and superior image quality. The 24- substrate slide 910AL scanner features high resolution 0.5 µm scanning,  three color 488 nm, 532 nm and 635 nm detection, 24-slide autoloader, high speed 3.5 min per slide 10 µm scan time, reliable and traceable results with barcode reading, comprehensive Mapix image quantification and analysis software, and proprietary high-speed Arrayit BioBlue Computer to manage the 22.96 GB data files produced by 0.5 µm scanning, 22” LED screen, keyboard, mouse, mouse pad, calibration slide and cables.

1100AL

$105,600
Purchase1

Arrayit InnoScan® 910 Microarray Scanner Warranty

Arrayit® InnoScan® 910 scanners are ideal instruments for scanning most low-, medium- and high-density microarrays available on the market, offering user-friendly software, competitive pricing and superior image quality. The warranty provides comprehensive coverage for one year on instruments operated in a normal manner. Warranty coverage is highly recommended for all users as non-warranty repairs often exceed the cost of the annual warranty.

910W

$7,690
Purchase1

Arrayit InnoScan® 910AL Microarray Scanner Warranty

Arrayit® InnoScan® 910AL scanners are ideal automated instruments for scanning most low-, medium- and high-density microarrays available on the market, offering user-friendly software, competitive pricing and superior image quality. The warranty provides comprehensive coverage for one year on instruments operated in a normal manner. Warranty coverage is highly recommended for all users as non-warranty repairs often exceed the cost of the annual warranty.

910ALW

$9,158
Purchase1

Arrayit InnoScan® 1100AL Microarray Scanner Warranty

Arrayit® InnoScan® 1100AL scanners are the ultimate automated instruments for scanning most low-, medium- and high-density microarrays available on the market, offering user-friendly software, competitive pricing and superior image quality. The warranty provides comprehensive coverage for one year on instruments operated in a normal manner. Warranty coverage is highly recommended for all users as non-warranty repairs often exceed the cost of the annual warranty.

1100ALW

$10,560
Purchase1

Mapix® Quantification and Analysis Software

Arrayit InnoScan® Mapix Microarray Controller, Quantification and Analysis Software for InnoScan 710, 710IR, 710AL, 710IRAL, 910, 910AL and 1100AL Microarray Scanners features advanced instrument control, automatic spot finding and detailed statistical outputs, price per software seat.

MAPIX

$4,879
Purchase1

*Please contact us directly for product pricing by email arrayit@arrayit.com, telephone 408.744.1331, or FAX 408.744.1711, or click on the purchase buttons above to proceed directly to the purchase pages.

*International pricing may vary as much as 30% or more depending on country due to import duties, stocking fees and technical support.

*Add shipping and handling to all orders.

Warranty
ArrayIt® InnoScan® brand products are sold for research purposes. Extreme care and exact attention should be practiced in the use of the products described herein. Arrayit products are subjected to extensive quality control and are guaranteed to perform as described when used properly. Any problems with these products should be reported to Arrayit immediately. Our liability is limited to the replacement of the product, or a full refund. Any misuse of this product is the full responsibility of the user, and Arrayit makes no warranty or guarantee under such circumstances.

 

 

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