Arrayit Corporation Logo

Arrayit Corporation (ARYC) leads and empowers the genetic, research, pharmaceutical, and diagnostic communities through the discovery, development and manufacture of proprietary life science technologies and consumables for disease prevention, treatment and cure.  - Powerful Science for Life™

Products - Microarray Scanners - Laser Scanners- Arrayit InnoScan® 710 Series High-Speed High-Resolution Two-Color Microarray Fluorescence Scanners

Microarray_Scanning
Arrayit offers the InnoScan 710 and 710AL, the world’s latest next generation microarray scanners with greater sensitivity and lower background, proprietary rotary motion control, dynamic auto-focusing, 2-color fluorescence detection, 3 µm scan resolution, 3 minute scan times and complete software. The new infrared 710IR and 710IRAL enable infrared microarray detection.

Product description

  • Latest next generation microarray scanning technology
  • Fastest and most compact microarray scanners available
  • Proprietary rotary scanning architecture permits the fastest scanning speeds
  • 3 minutes to scan an entire 25 x 76 mm substrate slide
  • Scan 24 substrate slides in 100 minutes using the 710AL
  • Adjustable scan resolution from 3 µm to 40 µm
  • Ideal for both in situ and ex situ microarrays
  • 710 and 710AL detect 532 nm (cyanine 3) and 635 nm (cyanine 5)
  • 710IR and 710IRAL detect 670 nm (cyanine 5.5) and 785 nm (infrared dye)
  • Compatible IR dyes: IRDye 800 RS (Li-Cor), DyLight 800 (Pierce) and Alexa Fluor 790 (Invitrogen)
  • Rotary scanning architecture reduces vibrational noise and increases image quality
  • Much greater reliability and longevity than conventional raster scanners
  • High resolution acquisition system: scans spot sizes down to 30 µm diameter
  • Real-time image acquisition for all microarray types including but not limited to in-situ high density glass slide microarrays, spotted microarrays of all kinds, tissue and cell microarrays
  • Low background noise and high sensitivity system
  • Uniform scanning across the entire microarray surface regardless of substrate type (glass, membrane and plastic)
  • Not sensitive to shocks, vibrations and slide deformation (portable)
  • Delivered with Mapix® software: an easy to use data acquisition and image analysis software including automatic spot recognition and powerful image analysis
  • Software for various OS environments (Linux, Windows )
  • Ethernet interface allows easy data sharing (scanner can be shared over network by several users)
  • Affordable price, low maintenance
  • Lightweight, robust structure makes it portable system
  • Small footprint for laboratory space saving
  • Weight: 15 kg

Image acquisition and quantification demo available upon request, email us at arrayit@arrayit.com.

Specifications

Lasers

Thermoelectrically cooled laser diodes with stabilized feedback output

Excitation wavelengths

532 and 635 nm (710 and 710AL); 670 and 785 nm (710IR and 710IRAL)

Laser power

Adjustable (2 laser power settings available)

Gain PMT

Linear from 0 to 100%

Autofocus

Real-time and automated

Detection

True confocal and high performances digital laser/PMT system

Optical resolution

3 µm

Pixel size

3 µm to 40 µm

Scanning time

3.5 min per 22 x 74 mm substrate at 10 µm resolution

Autoloader capacity

24 standard 25 x 76 mm glass substrate slides

Autoloader speed

5 seconds load/unload per substrate slide

Autoloader throughput

100 min for 24 substrate slides

Scan area

Full substrate slide area (22 x 74 mm)

Image format

Standard TIFF (16 bit gray scale)

Barcode reader

All formats

Power supply

88 - 264 VAC

Size (L x D x H)

28 x 46 x 37 cm (model 710); 33 x 60 x 42 cm (model 710AL)

Weight

16 Kg (model 710 and 710IR); 27 Kg (model 710AL and 710IRAL)

Class

Class I laser product

Sensitivity

0.05 fluor/µm˛

Dynamic range

>10,000-fold

Uniformity

<5% CV

Format

Open platform glass substrate slides (25 x 76 mm)

Computer interface

Ethernet

Image analysis

Highly accurate grid positioning using automatic spot recognition provide accurate quantification and 16-bit exportable TIFF data

Compatible fluorophores:

Cy5.5 (685 nm); Cy5, Alexa 647, Alexa 660 (635 nm); Cy3, Alexa 546, Alexa 555 (532 nm); 785 nm infrared dyes, and custom wavelengths available

microarray_scanner_autofocus
Figure 1. The ArrayIt® InnoScan® 710 microarray scanners use dynamic auto focusing, which greatly reduces background noise and increases signal intensities. This proprietary auto-focusing technology allows the system to adjust to temperature changes, mechanical perturbations and other system changes that would otherwise cause fluctuations in signal and background. The result is highly uniform scanning across the entire chip surface and consistent performance scan after scan.

Quantitation and analysis software is included with every scanner:
Mapix® is a microarray image analysis software application that is both intuitive and easy to use, combining imaging and analysis tools for superior performance.

Highly efficient algorithms provide rapid and effective feature gridding through automatic spot searching and optimal grid alignment.

microarray_grid

  • Automatic spot segmentation ensures high-quality experiment data by selecting relevant pixels and eliminating unwanted ones.
  • Gridding performance and quantification process are adapted to the high resolution of the InnoScan 710 (3 µm) and therefore to the size of images generated.
  • Optimal data visualization and quick learning thanks to its highly interactive commands, with full correlation between displayed data, pictures and plots.
  • Compatible all types of microarrays made by ex-situ and in-situ techniques.
  • Reads and analyzes interstitial/staggered/orange packing patterned microarrays made by the Protein NanoPrint, Agilent and others.

microarray_quantitation_software

  • Batch processing allows analysis of a large number of microarrays per day to boost productivity (available on Version 3.0.0).
  • Regular software updates are accessible on line to match evolving needs of customers (updates are free for the 1st year).

Configurable for full or modular automation of:

  • Scanner control
  • Configuration saving (scan and analysis parameters)
  • Bar code reading
  • Quality control by flagging

Compatible with all industry-standard formats and platforms:

  • Support GAL files and recordable transcripts in both text and GPR formats.
  • Images are saved as 16-bit TIFF images with all read parameters and can be copied in JPEG format.
  • Supports image analysis of 16-bit TIFF files from a variety of other scanners.
  • Platform-independent and runs on all operating systems (Windows, 32- and 64-bit Linux and Macintosh).

Arrayit InnoScan 710AL
Figure 2. The ArrayIt® InnoScan® 710AL laser microarray scannerwith autoloader provides high resolution, high-speed fluorescence scanning of all standard glass microarrays. The 710AL scans 24 glass substrate slides (25 x 76 mm) in both channels at 10 µm resolution in 100 minutes. The ArrayIt® InnoScan® 710AL laser microarray scanner is the perfect automated solution to high-throughput microarray scanning for research and diagnostics.

Ordering Information

Catalog ID

Description

Price (US dollars)*

710

ArrayIt® InnoScan® 710 simultaneous confocal 2-color fluorescence microarray scanner (532 nm and 635 nm) with 3 µm scan resolution, single substrate slide capacity, Mapix software, computer and monitor, one year warranty, and complimentary software upgrades for one year. Detects Cy3, Alexa 3, Alexa 546, Alexa 555, Cy5, Alexa 5, Alexa 647, and Alexa 660. Fully compatible with Arrayit microarrays and all major brands of open platform microarray products.

$46,032

710IR

ArrayIt® InnoScan® 710IR infrared simultaneous confocal 2-color fluorescence microarray scanner (670 nm and 785 nm) with 3 µm scan resolution, single substrate slide capacity, Mapix software, computer and monitor, one year warranty, and complimentary software upgrades for one year. Detects Cy5.5 and infrared 785 nm dyes. Fully compatible with Arrayit microarrays and all major brands of open platform microarray products.

$49,978

710AL

ArrayIt® InnoScan® 710AL simultaneous confocal 2-color fluorescence microarray scanner (532 nm and 635 nm) with 3 µm scan resolution, 24 substrate slide autoloader, Mapix software, computer and monitor, one year warranty, and complimentary software upgrades for one year. Detects Cy3, Alexa 3, Alexa 546, Alexa 555, Cy5, Alexa 5, Alexa 647, and Alexa 660. Fully compatible with Arrayit microarrays and all major brands of open platform microarray products.

$75,624

710IRAL

ArrayIt® InnoScan® 710IRAL infrared simultaneous confocal 2-color fluorescence microarray scanner (670 nm and 785 nm) with 3 µm scan resolution, 24 slide autoloader, Mapix software, computer and monitor, one year warranty, and complimentary software upgrades for one year. Detects Cy5.5 and infrared 785 nm dyes. Fully compatible with Arrayit microarrays and all major brands of open platform microarray products.

$79,570

ISA

ArrayIt® InnoScan® custom lasers, filter sets, optics, substrate holders and other custom accessories to accommodate laser scanning of diverse microarray substrates for novel microarray devices and assays.

$26,906

PWS710

One Year Warranty Extension for ArrayIt® InnoScan® 710 microarray scanners, covers parts and service for one year from the date of purchase.

$4,603

PWS710AL

One Year Warranty Extension for ArrayIt® InnoScan® 710AL microarray scanners, covers parts and service for one year from the date of purchase.

$7,562

MAPIX

ArrayIt® Mapix Microarray Controller, Quantification and Analysis Software for InnoScan 710, 710IR, 710AL and 710IRAL Microarray Scanners featuring advanced instrument control, automatic spot finding and detailed statistical outputs, price per software seat.

$4,879

AIC

Arrayit High-Performance Instrument Cleaner removes dust, particulates, fingerprints and other contaminants from InnoScan® Microarray Scanners. Apply using pump nozzle and Cleanroom Wipes, 65 ml of 1X solution.

$113

*Please contact us directly for product pricing by email arrayit@arrayit.com, telephone (408) 744-1331, or FAX (408) 744-1711, or click on the purchase buttons above to proceed directly to the purchase page.

*International pricing may vary as much as 30% (or more depending on country) due to import duties, stocking fees and technical support.

*Add shipping and handling to all orders.

Warranty
Arrayit ArrayIt® brand products are sold for research purposes. Extreme care and exact attention should be practiced in the use of the materials described herein. All Arrayit products are subject to extensive quality control and are guaranteed to perform as described when used properly. Any problems with these products should be reported to Arrayit immediately. Our liability is limited to the replacement of the product, or a full refund. Any misuse of this product is the full responsibility of the user, and Arrayit makes no warranty or guarantee under such circumstances.

 

Copyright 1993-2017 Arrayit Corporation. All rights reserved.