1 Micron Resolution Microarray Scanner

Products - Microarray Instruments - Microarray Laser Scanners - InnoScan 900 Series - 1 µm Resolution

Product Description

World’s only 1 µm microarray substrate slide scanner on the market.
Fast scanning system: proprietary slide motion control allows less than 4 minutes per slide scan time.
High resolution acquisition system: scans spot sizes from 5 micron and higher.
Real-time image acquisition for all microarray types including but not limited to in-situ high density glass slide microarrays, spotted microarrays of all kinds, tissue and cell microarrays.
Low background noise and high sensitivity system.
Uniform scanning across the entire microarray surface regardless of substrate type (glass, membrane and plastic).
Not sensitive to shocks, vibrations and slide deformation (portable).
Delivered with Mapix^® software: an easy to use data acquisition and image analysis software including automatic spot recognition and powerful image analysis71 974
Software for various OS environments (Linux, Windows ).
Ethernet interface allows easy data sharing (scanner can be shared over network by several users).
Affordable price, low maintenance.
Lightweight, robust structure makes it portable system.
Small footprint for laboratory space saving.

Specifications

Lasers

Thermoelectrically cooled laser diodes with stabilized feedback output

Excitation wavelengths

635 nm and 532 nm (900A and 900AL models)
635 nm (900R model)
532 nm (900G model)

Laser power

Adjustable to two different power settings

Gain PMT

0-100%

Autofocus

Real-time and automated

Detection

True confocal and high performances digital laser/PMT system

Optical resolution

1 µm

Pixel size

1 µm to 40 µm

Barcode reader

Yes

Scanning time

3.5 min per 22 x 70 mm substrate at 10 µm resolution

Autoloader capacity (optional)

24 standard 25 x 76 mm glass substrate slides

Autoloader speed

5 seconds load/unload per substrate slide

Autoloader throughput

100 min for 24 substrate slides

Scan area

Full substrate slide area (22 x 70 mm)

Image format

Standard TIFF (16 bit gray scale)

Barcode reader

All formats

Power supply

88 - 264 VAC

Size (L x D x H)

28.3 x 46 x 38.5 cm (models 900A, 900R and 900G)
33 x 60 x 42 cm (model 900AL)

Weight

17 Kg

Class

Class I laser product

Sensitivity

0.1 fluor/µm²

Dynamic range

>10,000-fold

Uniformity

<5% CV

Format

Open platform glass substrate slides (25 x 76 mm)

Computer interface

Ethernet

Image analysis

Highly accurate grid positioning using automatic spot recognition provide accurate quantification and 16-bit exportable TIFF data

Compatible fluorophores:

Cy5, Alexa 647, Alexa 660 (635 nm); Cy3, Alexa 546, Alexa 555 (532 nm); and custom wavelengths available

Click here to download the user manual for image acquisition and quantification.

Figure 1. The ArrayIt® InnoScan® 900 series scanners use dynamic auto focusing, which greatly reduces background noise and increases signal intensities. This proprietary auto-focusing technology allows the system to adjust to temperature changes, mechanical perturbations and other system changes that would otherwise cause fluctuations in signal and background. The result is highly uniform scanning across the entire chip surface and consistent performance scan after scan.

Quantitation and analysis software is included with every scanner
Mapix® is a microarray image analysis software application that is both intuitive and easy to use, combining imaging and analysis tools for superior performance.

Highly efficient algorithms provide rapid and effective feature gridding through automatic spot searching and optimal grid alignment.

Automatic spot segmentation ensures high-quality experiment data by selecting relevant pixels and eliminating unwanted ones.
Gridding performance and quantification process are adapted to the high resolution of the InnoScan 900 (1 micron) and therefore to the size of images generated.
Optimal data visualization and quick learning thanks to its highly interactive commands, with full correlation between displayed data, pictures and plots.
Compatible all types of microarrays made by ex-situ and in-situ techniques.
Reads and analyzes interstitial/staggered/orange packing patterned microarrays made by the NanoPrint, Agilent, Nimblegen and others.

Batch processing allows analysis of a large number of microarrays per day to boost productivity (available on Version 3.0.0).
Regular software updates are accessible on line to match evolving needs of customers (updates are free for the 1st year).

Configurable for full or modular automation of:

Scanner control
Configuration saving (scan and analysis parameters)
Bar code reading
Quality control by flagging

Compatible with all industry-standard formats and platforms:

Support GAL files and recordable transcripts in both text and GPR formats.
Images are saved as 16-bit TIFF images with all read parameters and can be copied in JPEG format.
Supports image analysis of 16-bit TIFF files from a variety of other scanners.
Platform-independent and runs on all operating systems (Windows, 32- and 64-bit Linux and Macintosh).

Figure 2. Up close view of the autoloader available on the InnoScan 900AL. Any number of microarrays can be loaded in any order.

Ordering Information

Catalog ID

Description

Price (US dollars)*

900AL

ArrayIt® simultaneous confocal 2-color fluorescence microarray scanner (635 nm and 532 nm) with 1 µm scan resolution, 24 substrate slide autoloader, Mapix software, computer and monitor, one year warranty, and complimentary software upgrades for one year. Detects Cy3, Alexa 546, Alexa 555, Cy5, Alexa 647, and Alexa 660. Fully compatible with every major brand of open platform microarray products.

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900A

ArrayIt® simultaneous confocal 2-color fluorescence microarray scanner (635 nm and 532 nm) with 1 µm scan resolution, single substrate slide capacity, Mapix software, computer and monitor, one year warranty, and complimentary software upgrades for one year. Detects Cy3, Alexa 546, Alexa 555, Cy5, Alexa 647, and Alexa 660. Fully compatible with every major brand of open platform microarray products.

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900R

ArrayIt® confocal single color fluorescence microarray scanner (635 nm) with 1 µm scan resolution, single substrate slide capacity, Mapix software, computer and monitor, one year warranty, and complimentary software upgrades for one year. Detects Cy5, Alexa 647, and Alexa 660. Fully compatible with every major brand of open platform microarray products.

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900G

ArrayIt® confocal single color fluorescence microarray scanner (532 nm) with 3 µm scan resolution, single substrate slide capacity, Mapix software, computer and monitor, one year warranty, and complimentary software upgrades for one year. Detects Cy3, Alexa 546, and Alexa 555. Fully compatible with every major brand of open platform microarray products.

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MAPIX

ArrayIt® Mapix Microarray Acquisition and Analysis Software for use with Arrayit InnoScan 700 Series Microarray Scanners and other glass substrate slide scanners that generate 16-bit quantifiable TIFF image data. The purchase price provides a single seat working on a single computer. Multiple seat licenses are available upon request. Please contact Arrayit directly for a quote.

6,000.00

Custom laser configurations are possible. Please contact us directly at arrayit@arrayit.com for more information.

Inquire

*Please contact us directly for product pricing by email arrayit@arrayit.com, telephone (408) 744-1331, or FAX (408) 744-1711.

*International pricing may vary as much as 30% (or more depending on country) due to import duties, stocking fees and technical support.

Warranty
TeleChem ArrayIt® brand products are sold for research purposes. Extreme care and exact attention should be practiced in the use of the materials described herein. All TeleChem products are subject to extensive quality control and are guaranteed to perform as described when used properly. Any problems with these products should be reported to TeleChem immediately. Our liability is limited to the replacement of the product, or a full refund. Any misuse of this product is the full responsibility of the user, and TeleChem makes no warranty or guarantee under such circumstances.